Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 14/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631786 | 1.00 | EPHX2 (0.69) | EPHX2ACHEADRA1APLA2G2APRMT1 | |
| SCHEMBL20663435 | 0.98 | EPHX2 (0.67) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL15551259 | 0.93 | ACHE (0.63) | EPHX2ACHE | |
| SCHEMBL19400416 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL3629434 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL19400363 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL3625938 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL19400357 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL19400387 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A | |
| SCHEMBL1077924 | 0.92 | EPHX2 (0.76) | EPHX2ACHEADRA1APLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |