Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830742 | 1.00 | TGM2 (0.50) | TGM2PPARAPPARGNAALAD2CTSL | |
| SCHEMBL1111208 | 0.90 | PPARA (0.55) | PPARAPPARGCTSLCTSBCTSS | |
| SCHEMBL376362 | 0.90 | PPARA (0.55) | PPARAPPARGCTSLCTSBCTSS | |
| SCHEMBL1111209 | 0.90 | PPARA (0.55) | PPARAPPARGCTSLCTSBCTSS | |
| SCHEMBL9832156 | 0.89 | TGM2 (0.63) | TGM2PPARAPPARGCTSLCTSK | |
| SCHEMBL9832150 | 0.89 | TGM2 (0.63) | TGM2PPARAPPARGCTSLCTSK | |
| SCHEMBL8814463 | 0.87 | NAALAD2 (0.64) | TGM2PPARAPPARGNAALAD2MME | |
| SCHEMBL7515531 | 0.81 | FOLH1 (0.58) | TGM2PPARAPPARGCTSLCTSS | |
| SCHEMBL221300 | 0.81 | ECE1 (0.65) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL1702159 | 0.81 | ECE1 (0.65) | CTSLCTSBCTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |