Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.63 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832156 | 1.00 | TGM2 (0.63) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL9830567 | 0.89 | TGM2 (0.63) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL9830564 | 0.89 | TGM2 (0.63) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL9830742 | 0.89 | TGM2 (0.50) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL9830736 | 0.89 | TGM2 (0.50) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL1111208 | 0.87 | PPARA (0.55) | CTSKCTSLPPARAPPARGSIRT2 | |
| SCHEMBL1111209 | 0.87 | PPARA (0.55) | CTSKCTSLPPARAPPARGSIRT2 | |
| SCHEMBL376362 | 0.87 | PPARA (0.55) | CTSKCTSLPPARAPPARGSIRT2 | |
| SCHEMBL9829700 | 0.85 | TGM2 (0.59) | TGM2CTSKCTSLPPARAPPARG | |
| SCHEMBL9829710 | 0.85 | TGM2 (0.59) | TGM2CTSKCTSLPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |