Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.61 |
| ▸ | ITGAL | P20701 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658536 | 0.87 | CA1 (0.71) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL9830755 | 0.87 | CA1 (0.62) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL12331113 | 0.86 | CA2 (0.52) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL4525493 | 0.85 | CA1 (0.72) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL19781406 | 0.84 | CA1 (0.59) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL9830947 | 0.82 | MME (0.57) | ITGB2ICAM1ITGALFNTAFNTB | |
| SCHEMBL16673386 | 0.81 | ITGB2 (0.51) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL11158707 | 0.81 | ITGB2 (0.58) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL6806998 | 0.80 | ITGB2 (0.62) | CA2CA1ITGB2ICAM1ITGAL | |
| SCHEMBL16673388 | 0.80 | ITGB2 (0.49) | CA2CA1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036832-C | Composition containing a penem or carbapenem artibiotic and the use of the same | SANKYO CO (JP) | 1997-12-31 | — | — | CN | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |