Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705543 | 0.94 | HSD11B1 (0.62) | HSD11B1TRPA1 | |
| SCHEMBL4611901 | 0.92 | HSD11B1 (0.56) | HSD11B1TRPA1 | |
| SCHEMBL9830541 | 0.90 | HSD11B1 (0.58) | HSD11B1TRPA1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9832170 | 0.89 | HSD11B1 (0.54) | HSD11B1TRPA1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9830651 | 0.88 | HSD11B1 (0.54) | HSD11B1 | |
| SCHEMBL9829989 | 0.87 | HSD11B1 (0.53) | HSD11B1TRPA1 | |
| SCHEMBL9831595 | 0.86 | HSD11B1 (0.56) | HSD11B1TRPA1 | |
| SCHEMBL9831027 | 0.86 | HSD11B1 (0.50) | HSD11B1TRPA1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL8304887 | 0.85 | HSD11B1 (0.55) | HSD11B1ALDH1A1KDM4E | |
| SCHEMBL6781711 | 0.85 | HSD11B1 (0.48) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | claimed |
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0185256-A2 | Triazole derivates, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |