Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | IL2 | P60568 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832511 | 0.84 | CDK5 (0.55) | ALDH1A1IDEKDM4ESMN1; SMN2CDK5 | |
| SCHEMBL9830880 | 0.83 | CDK5 (0.52) | ALDH1A1TLR7KDM4EMEN1KMT2A | |
| SCHEMBL9830869 | 0.81 | ROCK1 (0.54) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9823502 | 0.80 | TLR7 (0.65) | ALDH1A1TLR7IDEMAPK1MAPK10 | |
| SCHEMBL9830713 | 0.78 | HDAC6 (0.52) | TLR7MAPK1 | |
| SCHEMBL9830549 | 0.78 | TP53 (0.45) | ALDH1A1MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL9829838 | 0.78 | RAB9A (0.49) | ALDH1A1TLR7KDM4EMEN1KMT2A | |
| SCHEMBL9829826 | 0.77 | RAB9A (0.49) | ALDH1A1TLR7KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9830487 | 0.76 | RAB9A (0.48) | ALDH1A1TLR7KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9832310 | 0.75 | MAPT (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |