Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831900 | 0.89 | CYP1A1 (0.45) | ROCK1CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL9831158 | 0.87 | CDC25A (0.49) | ROCK1CDK5CDK5R1ALDH1A1CCNA2 | |
| SCHEMBL9832511 | 0.86 | CDK5 (0.55) | ROCK1CDK5CDK5R1ALDH1A1CCNA2 | |
| SCHEMBL9830880 | 0.83 | CDK5 (0.52) | ROCK1CDK5CDK5R1ALDH1A1CCNA2 | |
| SCHEMBL9830542 | 0.82 | ALDH1A1 (0.66) | ROCK1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9829547 | 0.82 | SMN1; SMN2 (0.48) | ROCK1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9830862 | 0.81 | ALDH1A1 (0.54) | CDK5CDK5R1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9831306 | 0.81 | MAPT (0.49) | ROCK1ALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| Monoethanolamine SCHEMBL9830948 | 0.81 | CDC25A (0.44) | ROCK1CDK5CDK5R1ALDH1A1CCNA2 | |
| SCHEMBL9823455 | 0.80 | IRAK4 (0.59) | ROCK1ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |