Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.69 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830934 | 1.00 | CA2 (0.69) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL31661789 | 0.94 | CA2 (0.62) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL3082006 | 0.94 | CA2 (0.76) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL10668269 | 0.88 | CA2 (0.68) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL186937 | 0.88 | CA2 (0.68) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL186935 | 0.88 | CA2 (0.68) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL31069924 | 0.87 | CA2 (0.67) | CA2FOLH1CA1CA12CA9 | |
| Ammonia Solution, Strong SCHEMBL11218438 | 0.86 | CA2 (0.67) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL9716717 | 0.85 | ERAP2 (0.55) | CA2FOLH1CA1CA12CA9 | |
| SCHEMBL9716730 | 0.85 | ERAP2 (0.55) | CA2FOLH1CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |