Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830047 | 0.96 | SCN9A (0.34) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| Oxalic Acid SCHEMBL10672405 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4ETP53MAPK1KMT2A | |
| Oxalic Acid SCHEMBL9831207 | 0.81 | MAPT (0.40) | ALDH1A1KDM4ETP53MAPK1KMT2A | |
| SCHEMBL9830031 | 0.79 | MAPT (0.37) | ALDH1A1KDM4EKMT2AMAPTNQO2 | |
| Fumaric Acid SCHEMBL10671609 | 0.79 | ACHE (0.34) | DRD2DRD3ALDH1A1KMT2AMEN1 | |
| SCHEMBL9829526 | 0.77 | DRD2 (0.40) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL9829460 | 0.76 | MAPT (0.38) | ALDH1A1KDM4ETP53MAPK1KMT2A | |
| Oxalic Acid SCHEMBL9830413 | 0.76 | SMPD1 (0.42) | ALDH1A1KDM4ETP53MAPK1 | |
| Oxalic Acid SCHEMBL10859438 | 0.74 | CYP3A4 (0.37) | DRD2DRD3ALDH1A1KDM4ETP53 | |
| Oxalic Acid SCHEMBL10674415 | 0.74 | HRH3 (0.38) | DRD2DRD3ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |