Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329266 | 0.82 | MAPK1 (0.39) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL112422 | 0.79 | NCOA1 (0.63) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL10756496 | 0.77 | NCOA1 (0.61) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| Hydrogen Sulfide SCHEMBL27922694 | 0.77 | NCOA1 (0.61) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL28436320 | 0.77 | NCOA1 (0.61) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL6321993 | 0.77 | NCOA1 (0.61) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL28431579 | 0.77 | NCOA1 (0.61) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| Ethylene Glycol SCHEMBL29029323 | 0.76 | NCOA1 (0.55) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL3998875 | 0.75 | NCOA1 (0.53) | MAPK1TP53RAB9ANCOA1NCOA3 | |
| SCHEMBL294721 | 0.75 | ALDH1A1 (0.58) | MAPK1TP53RAB9ANCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| EP-2318474-B1 | COMPOUND HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES AND ITS PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| US-20150065725-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| WO-2010017896-A1 | COMPOUND HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES AND ITS PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2010-02-18 | — | — | WO | disclosed |
| US-20100025671-A1 | ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| WO-2009112854-A1 | COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES | MERCK PATENT GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-2094812-A1 | ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-09-02 | — | — | EP | disclosed |
| EP-2095690-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GmbH (DE) | 2009-09-02 | — | — | EP | disclosed |
| EP-2092794-A1 | PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME | MERCK PATENT GmbH (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009090423-A1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |
| WO-2008081178-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008078114-A1 | ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008078115-A1 | PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | MAPK1 807/4885TP53 3900/4885RAB9A 913/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | MAPK1 807/4885TP53 3900/4885RAB9A 913/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | MAPK1 807/4885TP53 3900/4885RAB9A 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.