Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034495 | 0.98 | SLC6A5 (0.51) | SLC6A5FFAR1FFAR4GPR84CES2 | |
| SCHEMBL8936404 | 0.98 | SLC6A5 (0.51) | SLC6A5FFAR1FFAR4GPR84CES2 | |
| SCHEMBL179793 | 0.98 | SLC6A5 (0.51) | SLC6A5FFAR1FFAR4GPR84CES2 | |
| SCHEMBL9719716 | 0.98 | SLC6A5 (0.51) | SLC6A5FFAR1FFAR4GPR84CES2 | |
| SCHEMBL9830115 | 0.95 | CES2 (0.46) | SLC6A5GPR84CES2 | |
| SCHEMBL9827876 | 0.93 | SLC6A5 (0.46) | SLC6A5GSRFFAR1GPR84RNPEP | |
| SCHEMBL9789515 | 0.89 | SLC6A5 (0.64) | SLC6A5FFAR1FFAR4MAPT | |
| SCHEMBL9789518 | 0.89 | SLC6A5 (0.64) | SLC6A5FFAR1FFAR4MAPT | |
| SCHEMBL28169404 | 0.89 | SLC6A5 (0.64) | SLC6A5FFAR1FFAR4MAPT | |
| SCHEMBL28322807 | 0.89 | SLC6A5 (0.64) | SLC6A5FFAR1FFAR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |