Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.48 |
| ▸ | PGC | P20142 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830830 | 0.93 | REN (0.49) | RENPGCPSMB1PSMB8PSMB9 | |
| SCHEMBL9831316 | 0.91 | REN (0.49) | RENPGC | |
| SCHEMBL9832617 | 0.88 | REN (0.48) | RENPGC | |
| SCHEMBL7443816 | 0.87 | REN (0.55) | RENPGC | |
| SCHEMBL9833160 | 0.87 | REN (0.51) | RENPGC | |
| SCHEMBL9833647 | 0.87 | REN (0.53) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL7363621 | 0.86 | REN (0.50) | RENPGC | |
| SCHEMBL9832584 | 0.86 | REN (0.53) | RENPGC | |
| SCHEMBL7359315 | 0.86 | REN (0.50) | RENPGC | |
| SCHEMBL9526718 | 0.83 | REN (0.56) | RENPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4826958-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |
| EP-0184855-A2 | Resin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-06-18 | — | — | EP | disclosed |