SCHEMBL9832584

SCHEMBL9832584

CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(=O)C(F)(F)[C@H](O)[C@@H](N)CC1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.53
▸ PGC P20142 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7443816 0.89 REN (0.55) RENPGC
SCHEMBL9831316 0.89 REN (0.49) RENPGC
SCHEMBL9830830 0.87 REN (0.49) RENPGC
SCHEMBL9832617 0.86 REN (0.48) RENPGC
SCHEMBL9831589 0.86 REN (0.48) RENPGC
SCHEMBL7363621 0.85 REN (0.50) RENPGC
SCHEMBL7359315 0.85 REN (0.50) RENPGC
SCHEMBL9833160 0.85 REN (0.51) RENPGC
SCHEMBL7271925 0.83 REN (0.57) RENPGC
SCHEMBL7386767 0.83 REN (0.57) RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258289-A4 PEPTIDE ANALOGS — 1991-01-02 — — EP disclosed
US-4826958-A HYPOTENSIVE AGENTS ABBOTT LABORATORIES (US) 1989-05-02 — — US disclosed
EP-0258289-A1 PEPTIDE ANALOGS ABBOTT LABORATORIES (US) 1988-03-09 — — EP disclosed
WO-1987004349-A1 PEPTIDE ANALOGS DELLARIA JOSEPH 1987-07-30 — — WO disclosed
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