Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 6/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339766 | 0.87 | TSHR (0.40) | L3MBTL1ABL1RIN1TDP1CYP1A2 | |
| SCHEMBL10867514 | 0.86 | CYP1A2 (0.44) | L3MBTL1ABL1RIN1TDP1CYP1A2 | |
| SCHEMBL5767349 | 0.80 | KAT2B (0.43) | L3MBTL1CYP1A2TSHRCHRM1ALDH1A1 | |
| SCHEMBL27065452 | 0.76 | ALDH1A1 (0.48) | L3MBTL1TDP1CYP1A2TSHRRAB9A | |
| SCHEMBL1127803 | 0.76 | PAOX (0.59) | L3MBTL1ABL1RIN1TDP1CYP1A2 | |
| SCHEMBL7418522 | 0.76 | CYP1A2 (0.50) | L3MBTL1CYP1A2RAB9AALDH1A1POLB | |
| SCHEMBL7715035 | 0.76 | ABCB1 (0.49) | L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL11861074 | 0.76 | CYP1A2 (0.53) | L3MBTL1TDP1CYP1A2TSHRRAB9A | |
| SCHEMBL4006818 | 0.75 | PAOX (0.62) | L3MBTL1TDP1CYP1A2TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL7418518 | 0.75 | ALDH1A1 (0.50) | L3MBTL1CYP1A2RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |