Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830864 | 0.90 | TSHR (0.38) | TSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL9832877 | 0.89 | ACLY (0.47) | ACLYTSHRALDH1A1HSD17B10KDM4E | |
| Flumetsulam SCHEMBL54906 | 0.89 | TSHR (0.40) | TSHRALDH1A1HTR6 | |
| SCHEMBL9833895 | 0.88 | ACLY (0.41) | ACLYTSHR | |
| Flumetsulam SCHEMBL20723449 | 0.88 | TSHR (0.39) | TSHRALDH1A1HTR6 | |
| Flumetsulam SCHEMBL20723426 | 0.88 | TSHR (0.39) | TSHRALDH1A1HTR6 | |
| SCHEMBL9831177 | 0.87 | TSHR (0.44) | TSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL9831887 | 0.87 | MEN1 (0.39) | ACLYTSHRALDH1A1 | |
| SCHEMBL9832951 | 0.86 | TSHR (0.34) | TSHRALDH1A1KAT6A | |
| SCHEMBL9832538 | 0.85 | TSHR (0.38) | TSHRALDH1A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |