Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663747 | 0.91 | ACLY (0.37) | ACLYPOLBTSHRALDH1A1HPGD | |
| SCHEMBL9833895 | 0.90 | ACLY (0.41) | ACLYTSHRHPGDSORT1MEN1 | |
| SCHEMBL9831464 | 0.89 | TSHR (0.39) | ACLYTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL9832052 | 0.89 | ACLY (0.36) | ACLYTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9833689 | 0.87 | ACLY (0.36) | ACLYMETAP2TSHRKDM4EALDH1A1 | |
| SCHEMBL9832726 | 0.86 | TP53 (0.40) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9831887 | 0.86 | MEN1 (0.39) | ACLYTSHRALDH1A1SORT1MEN1 | |
| SCHEMBL9833348 | 0.86 | ACLY (0.35) | ACLYMETAP2TSHRALDH1A1SORT1 | |
| SCHEMBL8355022 | 0.86 | TSHR (0.35) | ACLYTSHRALDH1A1HPGDMEN1 | |
| SCHEMBL9831761 | 0.84 | TSHR (0.35) | ACLYPOLBMETAP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |