Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832063 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL3923935 | 0.83 | POLB (0.50) | SMN1; SMN2LMNAGAAHSD17B10POLB | |
| SCHEMBL16245082 | 0.76 | POLB (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL2282705 | 0.76 | MAOA (0.48) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8707463 | 0.72 | CYP2C19 (0.48) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9829583 | 0.71 | CXCR2 (0.42) | LMNAKMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL9829581 | 0.71 | CXCR2 (0.42) | LMNAKMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL7454308 | 0.71 | HDAC8 (0.58) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL7784153 | 0.70 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL18112741 | 0.70 | KMT2A (0.43) | LMNAMEN1KMT2AHTTHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |