Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897832 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL6562939 | 0.98 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL8581694 | 0.98 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL9829273 | 0.98 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL7896986 | 0.98 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL6561332 | 0.97 | TSHR (0.53) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL25045739 | 0.97 | KMT2A (0.56) | ALDH1A1KMT2AMEN1LMNATSHR | |
| Benzene SCHEMBL28226142 | 0.95 | PSMB5 (0.55) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL7898101 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL1951893 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981394-A1 | A SORTILIN ANTAGONIST FOR USE IN THE PREVENTION OR TREATMENT OF HEARING LOSS. | Insusense ApS (DK) | 2022-04-13 | — | — | EP | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |