Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833394 | 0.85 | ALOX5 (0.74) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL9832972 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL9831303 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL2466643 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL8806200 | 0.73 | ALOX5 (1.00) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL8807104 | 0.72 | ALOX5 (0.68) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL13543173 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL12766564 | 0.72 | ALOX5 (0.61) | ALDH1A1TDP1ALOX5KMT2A | |
| SCHEMBL14654432 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL7416084 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTPKMHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |