Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051728 | 0.78 | REN (0.35) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL7589493 | 0.78 | REN (0.35) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL9832812 | 0.78 | REN (0.35) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL7440693 | 0.77 | REN (0.38) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL7440684 | 0.77 | REN (0.38) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL17789278 | 0.74 | METAP1 (0.40) | CTSKCTSLCTSBSLC1A3SLC1A2 | |
| SCHEMBL30415115 | 0.74 | METAP1 (0.40) | CTSKCTSLCTSBSLC1A3SLC1A2 | |
| SCHEMBL9831663 | 0.73 | REN (0.38) | CTSKCTSLCTSBSLC1A3SLC1A2 | |
| SCHEMBL7589499 | 0.73 | REN (0.36) | CTSKCTSLCTSBCTSHREN | |
| SCHEMBL7051735 | 0.73 | REN (0.36) | CTSKCTSLCTSBCTSHREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |