Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440684 | 1.00 | REN (0.38) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL7361728 | 0.84 | SLC1A3 (0.37) | METAP1METAP2ALOX5 | |
| SCHEMBL10354798 | 0.84 | SLC1A3 (0.37) | METAP1METAP2ALOX5 | |
| SCHEMBL10768614 | 0.84 | SLC1A3 (0.37) | METAP1METAP2ALOX5 | |
| SCHEMBL30415115 | 0.78 | METAP1 (0.40) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL17789278 | 0.78 | METAP1 (0.40) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL7589499 | 0.78 | REN (0.36) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL7051735 | 0.78 | REN (0.36) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL7051728 | 0.77 | REN (0.35) | RENCTSLCTSBCTSHMETAP1 | |
| SCHEMBL9832260 | 0.77 | CTSK (0.36) | RENCTSLCTSBCTSHMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |