SCHEMBL9832291

SCHEMBL9832291

[CH]=Cc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
HSD17B10 Q99714 5/20 0.62
ALOX12 P18054 5/20 0.62
L3MBTL1 Q9Y468 5/20 0.62
TSHR P16473 4/20 0.62
TDP1 Q9NUW8 4/20 0.62
ALOX15 P16050 2/20 0.62
MAPK1 P28482 2/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
MAPT P10636 6/20 0.50
CYP3A4 P08684 5/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3372676 0.80 ALDH1A1 (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL3374038 0.80 ALDH1A1 (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL42930 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL7896372 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL13663470 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL9480038 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL465276 0.78 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL465277 0.78 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL11140723 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL510414 0.76 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304613-B1 BENZOPYRAN DERIVATIVES BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
US-4958021-A PRESSURE AND HEAT SENSITIVE RECORDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1990-09-18 US disclosed
EP-0304613-A1 Benzopyran derivatives BASF Aktiengesellschaft (DE) 1989-03-01 EP disclosed