SCHEMBL465277

SCHEMBL465277

C(=Cc1ccc(Nc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
HSD17B10 Q99714 4/20 0.65
ALOX12 P18054 3/20 0.65
L3MBTL1 Q9Y468 3/20 0.65
ALOX15 P16050 2/20 0.65
TSHR P16473 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
PTGS1 P23219 1/20 0.65
SLC6A2 P23975 1/20 0.65
MAPK1 P28482 1/20 0.65
PTGS2 P35354 1/20 0.65
HTR2B P41595 1/20 0.65
SIRT2 Q8IXJ6 1/20 0.53
CYP3A4 P08684 3/20 0.52
MAPT P10636 2/20 0.52
MAOB P27338 2/20 0.52
HPGD P15428 2/20 0.52
NFE2L2 Q16236 1/20 0.52
CYP19A1 P11511 1/20 0.52
MAOA P21397 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465276 1.00 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL7782610 0.97 HSD17B10 (0.63) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL3372676 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL293235 0.97 ALDH1A1 (0.60) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL3374038 0.97 ALDH1A1 (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL10042620 0.97 ALDH1A1 (0.60) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
(Z)-1,2-Diphenylethene SCHEMBL1877462 0.95 HSD17B10 (0.67) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL14570386 0.91 MAOB (0.64) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
SCHEMBL13863540 0.91 MAOB (0.64) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL4735870 0.91 HSD17B10 (0.55) ALDH1A1HSD17B10ALOX12L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021152940-A1 COMPOUND, ORGANIC THIN-FILM LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE 東レ株式会社 2021-08-05 WO disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
EP-1730101-B1 ALKYLATED PANA AND DPA COMPOSITIONS BASF SE (DE) 2015-11-18 EP disclosed
US-9181378-B2 Modified natural rubber and method of manufacturing the same, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2015-11-10 US disclosed
US-9132697-B2 Modified natural rubber or modified natural rubber latex, and rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2015-09-15 US disclosed
EP-1215226-B1 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR CORP (JP) 2006-06-07 EP disclosed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP disclosed
US-20050182159-A1 Diene rubber-inorganic compound composite and process for producing the same JRS CORPORATION (JP) 2005-08-18 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-6740704-B2 UNIFORM DISPERSION JSR CORPORATION (JP) 2004-05-25 US disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed
US-20020111418-A1 Methods for producing diene-based rubber/inorganic compound complexes and rubber compositions containing the same JSR CORPORATION (JP) 2002-08-15 US disclosed
EP-1215226-A2 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR Corporation (JP) 2002-06-19 EP disclosed