Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830814 | 0.88 | HSD11B1 (0.54) | HSD11B1TRPA1 | |
| SCHEMBL9829439 | 0.88 | HSD11B1 (0.56) | HSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL9831676 | 0.88 | HSD11B1 (0.53) | HSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL9830541 | 0.86 | HSD11B1 (0.58) | HSD11B1TRPA1 | |
| SCHEMBL9832170 | 0.82 | HSD11B1 (0.54) | HSD11B1TRPA1 | |
| SCHEMBL9831027 | 0.82 | HSD11B1 (0.50) | HSD11B1TRPA1 | |
| SCHEMBL9829855 | 0.81 | HSD11B1 (0.53) | HSD11B1TRPA1 | |
| SCHEMBL9830769 | 0.81 | HSD11B1 (0.53) | HSD11B1TRPA1 | |
| SCHEMBL9830395 | 0.81 | HSD11B1 (0.66) | HSD11B1TRPA1TRPM8TRPV1S1PR1 | |
| SCHEMBL9705543 | 0.80 | HSD11B1 (0.62) | HSD11B1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0185256-A2 | Triazole derivates, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |