SCHEMBL9830769

SCHEMBL9830769

Cn1nc(-c2ccc(F)cc2F)nc1-c1ccccc1C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 19/20 0.53
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9829855 0.88 HSD11B1 (0.53) HSD11B1TRPA1
SCHEMBL9831021 0.88 HSD11B1 (0.42) HSD11B1
SCHEMBL9830639 0.88 HSD11B1 (0.67) HSD11B1
SCHEMBL9829408 0.88 HSD11B1 (0.67) HSD11B1
SCHEMBL9830811 0.86 HSD11B1 (0.48) HSD11B1TRPA1
SCHEMBL9830541 0.85 HSD11B1 (0.58) HSD11B1TRPA1
SCHEMBL9829686 0.83 HSD11B1 (0.50) HSD11B1TRPA1
SCHEMBL9831028 0.82 HSD11B1 (0.37) HSD11B1
SCHEMBL9830814 0.81 HSD11B1 (0.54) HSD11B1TRPA1
SCHEMBL9832170 0.81 HSD11B1 (0.54) HSD11B1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0185256-B1 TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES CIBA-GEIGY AG (CH) 1991-01-30 EP claimed
US-4788210-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US claimed
EP-0185256-B1 TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES CIBA-GEIGY AG (CH) 1991-01-30 EP disclosed
US-4788210-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed