Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11131297 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL13113794 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL19433081 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL14397608 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL19733328 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL19713060 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL19733325 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL4704147 | 0.71 | — | — | |
| SCHEMBL13560836 | 0.70 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL19713076 | 0.70 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| EP-0211665-A2 | Benzoyl-ureas having acaricide and insecticide activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-02-25 | — | — | EP | disclosed |