Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833157 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1LMNAMAPTHPGD | |
| SCHEMBL29300462 | 0.68 | NOS3 (0.34) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11203763 | 0.65 | TSHR (0.39) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11198362 | 0.65 | TSHR (0.39) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11203765 | 0.65 | TSHR (0.39) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL28743413 | 0.64 | ALDH1A1 (0.39) | ALDH1A1MEN1LMNAMAPTHPGD | |
| SCHEMBL9655502 | 0.64 | KMT2A (0.36) | ALDH1A1LMNAMAPTKMT2ANOS3 | |
| SCHEMBL426485 | 0.64 | KMT2A (0.36) | ALDH1A1LMNAMAPTKMT2ANOS3 | |
| SCHEMBL7014493 | 0.64 | KMT2A (0.36) | ALDH1A1LMNAMAPTKMT2ANOS3 | |
| SCHEMBL8344822 | 0.64 | KMT2A (0.36) | ALDH1A1LMNAMAPTKMT2ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110548-A1 | PROCESS FOR DIASTEREOSELECTIVE ALKYLATION OF THE OXIME ETHER OF THE COMPOUND NOPINONE, AND NEW INTERMEDIATES FOR THE SYNTHESIS OF DIASTEREOSPECIFIC 2-AMINO-NOPINONE DERIVATIVES SUBSTITUTED ON THE 3 CARBON | PPG-SIPSY (FR) | 2007-10-04 | — | — | WO | disclosed |