Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316010 | 0.72 | — | — | |
| SCHEMBL11758351 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL245746 | 0.65 | — | — | |
| SCHEMBL756149 | 0.61 | — | — | |
| SCHEMBL5520507 | 0.61 | — | — | |
| SCHEMBL5526003 | 0.61 | ALDH1A1 (0.33) | — | |
| SCHEMBL3321786 | 0.61 | — | — | |
| SCHEMBL21313359 | 0.59 | LMNA (0.30) | — | |
| SCHEMBL29289457 | 0.59 | — | — | |
| SCHEMBL13355830 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| EP-0069424-B1 | PROCESS FOR THE SELECTIVE REDUCTION OF A 14, 17-DIOXO-8,4-SECO-STEROID | AKZO N.V. (NL) | 1985-05-29 | — | — | EP | disclosed |