Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641492 | 0.78 | HSD11B1 (0.53) | HSD11B1SIGMAR1HSD17B2FAAHOPRM1 | |
| SCHEMBL28332692 | 0.77 | HSD11B1 (0.49) | HSD11B1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9985679 | 0.75 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL959486 | 0.74 | HSD11B1 (0.69) | HSD11B1OPRM1OPRK1 | |
| SCHEMBL3644756 | 0.74 | HSD11B1 (0.69) | HSD11B1OPRM1OPRK1 | |
| SCHEMBL3645417 | 0.74 | HSD11B1 (0.69) | HSD11B1OPRM1OPRK1 | |
| SCHEMBL10441281 | 0.74 | MAPT (0.50) | HSD11B1SIGMAR1POLBACHEOPRM1 | |
| SCHEMBL17912905 | 0.74 | ROCK2 (0.50) | HSD11B1POLBROCK2KCNH2 | |
| SCHEMBL17912904 | 0.74 | ROCK2 (0.50) | HSD11B1POLBROCK2KCNH2 | |
| SCHEMBL16429900 | 0.74 | HSD11B1 (0.52) | HSD11B1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |