Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972585 | 0.85 | GAA (0.43) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL4971473 | 0.85 | GAA (0.43) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL4969967 | 0.83 | GAA (0.41) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL14011490 | 0.80 | GAA (0.47) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL7264782 | 0.77 | GAA (0.47) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL4753064 | 0.77 | GAA (0.47) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL13636231 | 0.77 | GAA (0.47) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL14037661 | 0.76 | CA1 (0.51) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL22338809 | 0.76 | CA1 (0.51) | CYP2D6GAAHDAC4HDAC1HDAC6 | |
| SCHEMBL6477906 | 0.76 | CTSK (0.44) | CYP2D6GAAHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437508-A4 | NON-PEPTIDE RENIN INHIBITORS | — | 1991-11-06 | — | — | EP | disclosed |