Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487089 | 1.00 | SPHK1 (0.50) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL6354275 | 1.00 | SPHK1 (0.50) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL732145 | 0.96 | MAPT (0.46) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL25422946 | 0.90 | MAPT (0.42) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL24053312 | 0.90 | SPHK1 (0.48) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL6445059 | 0.86 | GPR84 (0.46) | SPHK1MAPTTRPA1DDAH1GAPDH | |
| SCHEMBL6358091 | 0.85 | TSHR (0.45) | SPHK1CYP2D6MAPTGMNNLMNA | |
| SCHEMBL8897164 | 0.84 | ADH1B (0.50) | MAPTLMNATRPA1DDAH1GAPDH | |
| SCHEMBL6030603 | 0.84 | ADH1B (0.50) | MAPTLMNATRPA1DDAH1GAPDH | |
| SCHEMBL17813925 | 0.83 | MEN1 (0.42) | SPHK1CYP2D6MAPTGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262255-B1 | ACRYLOXYMETHYL SUBSTITUTED FATTY COMPOUNDS | HENKEL CORPORATION (a Delaware corp.) (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0262255-A1 | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (a Delaware corp.) (US) | 1988-04-06 | — | — | EP | disclosed |
| EP-0208921-A2 | Hydroformylation of olefinic compounds in the presence of soluble cobalt salt catalysts and an organic nitrile promoter | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4626582-A | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| US-4413138-A | Glycidyl ethers of aminopolyols | HENKEL CORPORATION (US) | 1983-11-01 | — | — | US | disclosed |