Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835339 | 0.90 | ATAD2 (0.42) | ATAD2MAPK14PGRPDE3BPDE3A | |
| SCHEMBL9834460 | 0.82 | ATAD2 (0.42) | ATAD2MAPK14PGRPDE3BPDE3A | |
| SCHEMBL9834909 | 0.74 | ATAD2 (0.42) | ATAD2PGRKDM4EALDH1A1HPGD | |
| SCHEMBL9835634 | 0.74 | ATAD2 (0.44) | ATAD2PGRPDE3BPDE3APDE4A | |
| SCHEMBL9835182 | 0.73 | ATAD2 (0.49) | ATAD2MAPK14PGRPDE3BPDE3A | |
| SCHEMBL10662924 | 0.72 | ATAD2 (0.40) | ATAD2MAPK14PGRPDE3BPDE3A | |
| SCHEMBL2489476 | 0.71 | ATAD2 (0.42) | ATAD2PGRPDE3BPDE3APDE4A | |
| SCHEMBL9834972 | 0.71 | ATAD2 (0.50) | ATAD2PGRPDE3BPDE3APDE4A | |
| SCHEMBL9834421 | 0.71 | ALDH1A1 (0.41) | MAPK14PGRKDM4EALDH1A1GAA | |
| SCHEMBL9833315 | 0.70 | ATAD2 (0.41) | ATAD2MAPK14PGRPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |