Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835813 | 0.88 | ATAD2 (0.31) | ATAD2PGRIDO1 | |
| SCHEMBL9835874 | 0.86 | ATAD2 (0.30) | ATAD2PGR | |
| SCHEMBL9833702 | 0.86 | ATAD2 (0.30) | ATAD2PGR | |
| SCHEMBL9833058 | 0.84 | — | — | |
| SCHEMBL9834751 | 0.84 | — | — | |
| SCHEMBL9834492 | 0.84 | KDM4E (0.34) | KMT2A | |
| SCHEMBL9833669 | 0.82 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL9834931 | 0.81 | NQO2 (0.31) | PGR | |
| SCHEMBL9834998 | 0.80 | TNKS2 (0.40) | KMT2APGR | |
| SCHEMBL9835182 | 0.80 | ATAD2 (0.49) | ATAD2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |