Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834460 | 0.86 | ATAD2 (0.42) | — | |
| SCHEMBL9834678 | 0.84 | TP53 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9835813 | 0.82 | ATAD2 (0.31) | — | |
| SCHEMBL9833591 | 0.82 | KMT2A (0.32) | — | |
| SCHEMBL9833702 | 0.81 | ATAD2 (0.30) | — | |
| SCHEMBL9835874 | 0.81 | ATAD2 (0.30) | — | |
| SCHEMBL9833058 | 0.79 | — | — | |
| SCHEMBL9834931 | 0.77 | NQO2 (0.31) | — | |
| SCHEMBL9834998 | 0.76 | TNKS2 (0.40) | SMN1; SMN2 | |
| SCHEMBL9835229 | 0.75 | PGR (0.31) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |