Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metronidazole SCHEMBL6053140 | 0.80 | LMNA (0.86) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL5885668 | 0.80 | LMNA (0.97) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL9531382 | 0.80 | KMT2A (0.42) | LMNATHRBCA1CA2CA9 | |
| Metronidazole SCHEMBL21293782 | 0.78 | LMNA (0.94) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL29168722 | 0.78 | LMNA (0.94) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL9460595 | 0.78 | LMNA (0.94) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL28233371 | 0.78 | LMNA (0.94) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL6911811 | 0.78 | LMNA (0.94) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL2221140 | 0.78 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL9455119 | 0.78 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324691-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-12-27 | — | — | EP | claimed |