Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833780 | 1.00 | MMP8 (0.55) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5420072 | 0.80 | FKBP1A (0.53) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5420082 | 0.80 | FKBP1A (0.53) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL6279409 | 0.80 | FKBP1A (0.53) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5955854 | 0.78 | FKBP1A (0.51) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5421925 | 0.78 | FKBP1A (0.51) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5421917 | 0.78 | FKBP1A (0.51) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL5955857 | 0.78 | FKBP1A (0.51) | MMP8FKBP1AALDH1A1TSHRPOLB | |
| SCHEMBL10419193 | 0.77 | GRIK1 (0.57) | MMP8MAPTLMNA | |
| SCHEMBL12196227 | 0.77 | FKBP1A (0.60) | MMP8FKBP1AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437508-A4 | NON-PEPTIDE RENIN INHIBITORS | — | 1991-11-06 | — | — | EP | disclosed |