Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833240 | 0.86 | HTT (0.58) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL13064782 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL9832426 | 0.78 | ALOX5 (0.71) | ALDH1A1KDM4EMAPTPOLBPKM | |
| SCHEMBL2181967 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL853606 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL151035 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL8814587 | 0.76 | ALOX5 (0.59) | ALDH1A1KDM4EMAPTALOX5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL245313 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL2093655 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL6240522 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |