Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832911 | 0.81 | PGR (0.40) | — | |
| SCHEMBL9834118 | 0.77 | PGR (0.44) | MAPTTP53LMNA | |
| SCHEMBL9833556 | 0.74 | — | — | |
| SCHEMBL9834194 | 0.73 | — | — | |
| SCHEMBL9835021 | 0.70 | CHRNB2 (0.43) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL9833926 | 0.70 | — | — | |
| SCHEMBL9834093 | 0.69 | MAOB (0.34) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL25761239 | 0.69 | MAPT (0.55) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL15723865 | 0.69 | MAPT (0.55) | MAOBMAPTTP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL10376017 | 0.69 | MAOB (0.40) | MAOBMAPTTP53LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257334-B1 | TRICYCLIC BENZOTRIAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1991-01-02 | — | — | EP | disclosed |
| US-4835167-A | Tricyclic benzotriazoles, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0257334-A2 | Tricyclic benzotriazoles, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |