Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216900 | 0.82 | CA2 (0.69) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL7337427 | 0.82 | CA2 (0.48) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL16443971 | 0.80 | CA2 (0.47) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL10451582 | 0.80 | CA2 (0.47) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL14018319 | 0.80 | CA2 (0.70) | CA2SMN1; SMN2ENPP2PTGS2CA12 | |
| SCHEMBL6798039 | 0.80 | CA2 (0.52) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL2045174 | 0.80 | CA2 (0.47) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL7339629 | 0.80 | CA2 (0.47) | CA2SMN1; SMN2ENPP2KCNJ1KCNH2 | |
| SCHEMBL1943907 | 0.80 | CA2 (0.67) | CA2SMN1; SMN2ENPP2PTGS2CA12 | |
| SCHEMBL12040857 | 0.78 | CA2 (0.68) | CA2SMN1; SMN2ENPP2PTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193303-B1 | ALKENE, ALKYNE OR CYCLOALKYLENE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-23 | — | — | EP | claimed |
| EP-0193303-B1 | ALKENE, ALKYNE OR CYCLOALKYLENE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-23 | — | — | EP | disclosed |