SCHEMBL7216900

SCHEMBL7216900

CCCCc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
CA1 P00915 2/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 2/20 0.51
CA12 O43570 1/20 0.51
CA9 Q16790 1/20 0.51
TSHR P16473 1/20 0.51
HPGD P15428 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CNR2 P34972 1/20 0.49
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
POLB P06746 1/20 0.48
ATM Q13315 1/20 0.48
AKT1 P31749 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14018319 0.94 CA2 (0.70) CA2SMN1; SMN2CA1LMNAHTT
SCHEMBL12204115 0.92 CA2 (0.68) CA2SMN1; SMN2CA1LMNAHTT
SCHEMBL22792207 0.92 CA2 (0.68) CA2SMN1; SMN2CA1LMNAHTT
SCHEMBL12040857 0.92 CA2 (0.68) CA2SMN1; SMN2CA1LMNAHTT
SCHEMBL20883032 0.92 CA2 (0.68) CA2SMN1; SMN2CA1LMNAHTT
SCHEMBL6793165 0.87 CA2 (0.67) CA2SMN1; SMN2FFAR4LMNAHTT
SCHEMBL27790746 0.85 FFAR1 (0.76) FFAR1FFAR4LMNAHPGDPOLB
SCHEMBL10791903 0.85 CA2 (0.71) CA2SMN1; SMN2FFAR1FFAR4CA1
SCHEMBL27366281 0.83 CA2 (0.69) CA2SMN1; SMN2FFAR1FFAR4CA1
SCHEMBL10179705 0.83 CA2 (0.69) CA2SMN1; SMN2FFAR1FFAR4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119673-A Reactive dye and photosensitive composition using same 德山新勒克斯有限公司 2024-05-31 CN disclosed
CN-116909096-A Photosensitive composition for forming light shielding layer of organic light emitting display device 德山新勒克斯有限公司 2023-10-20 CN disclosed
CN-110297394-B Colored photosensitive resin composition, color filter and image display device 东友精细化工有限公司 2023-09-08 CN disclosed
CN-116144345-A Quantum dot-ligand complex, photosensitive resin composition, optical film, electroluminescent diode, and electronic device 德山新勒克斯有限公司 2023-05-23 CN disclosed
US-20230149549-A1 SMARCA DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-05-18 US disclosed
WO-2023023156-A1 ACID CERAMIDASE INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-02-23 WO disclosed
US-20220340570-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2022-10-27 US disclosed
EP-3553061-A1 NEW INHIBITORS OF BONE RESORPTION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2019-10-16 EP disclosed
CN-107272341-A Photomask photosensitive polymer combination, base plate for displaying and its manufacture method 新日铁住金化学株式会社 2017-10-20 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
EP-1539141-B1 3-(SULFONAMIDOETHYL)-INDOLE DERIVATIVES FOR USE AS GLUCOCORTICOID MIMETICS IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND PROLIFERATIVE DISEASES BOEHRINGER INGELHEIM PHARMA (US) 2010-07-14 EP disclosed
US-20090298878-A1 OXIME COMPOUNDS AND THE USE THEREOF PURDUE PHARMA L.P. 2009-12-03 US disclosed
WO-2008156715-A1 CETP INHIBITORS DERIVED FROM BENZOXAZOLE ARYLAMIDES MERCK & CO., INC. (US) 2008-12-24 WO disclosed
US-20080312229-A1 Organic Compounds NOVARTIS AG 2008-12-18 US disclosed
US-7375170-B2 Organosilicon compound CHISSO CORPORATION (JP) 2008-05-20 US disclosed
US-20030166687-A1 ALPHA-HYDROXY,-AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY 2003-09-04 US disclosed
EP-1037868-B1 $g(a)-HYDROXY, -AMINO, AND HALO DERIVATIVES OF $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS UPJOHN CO (US) 2003-02-05 EP disclosed
US-6437177-B1 DISEASES INVOLVING CONNECTIVE TISSUE DEGRADATION; ARTHRITIS, OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, DERMAL, OR GASTRIC ULCERATION, AND ASTHMA; 2-HYDROXY-2-(PHENYLTHIO) METHYL-3-(4-BUTOXYBENZENESULFONYL)PROPIONIC ACID PHARMACIA & UPJOHN COMPANY 2002-08-20 US disclosed
EP-1037868-A2 $g(a)-HYDROXY, -AMINO, AND HALO DERIVATIVES OF $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 2000-09-27 EP disclosed
WO-1999026909-A2 ALPHA-HYDROXY, -AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1999-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298878-A1 OXIME COMPOUNDS AND THE USE THEREOF KCNN4, CACNA1A, KCNN3 CA2 5/4885SMN1; SMN2 664/4885FFAR1 361/4885
US-20230149549-A1 SMARCA DEGRADERS AND USES THEREOF SMARCA1, SMARCB1, SMARCE1 CA2 4428/4885SMN1; SMN2 1122/4885FFAR1 4109/4885
US-20080312229-A1 Organic Compounds DRD4, DRD1, SLC10A6 CA2 1872/4885SMN1; SMN2 3169/4885FFAR1 656/4885
US-20030166687-A1 ALPHA-HYDROXY,-AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS MMP1, MMP8, HRH3 CA2 1634/4885SMN1; SMN2 3029/4885FFAR1 525/4885
US-20220340570-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 CA2 4617/4885SMN1; SMN2 2647/4885FFAR1 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.