Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830055 | 0.88 | CTSL (0.50) | ATMCTRB1CTSLCTSSCYP3A4 | |
| SCHEMBL11614466 | 0.87 | ATM (0.72) | ATMCTSLCTSSALDH1A1CYP3A4 | |
| SCHEMBL1362502 | 0.84 | ATM (0.77) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL3255533 | 0.84 | ATM (0.77) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL7719287 | 0.84 | ATM (0.77) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL434233 | 0.84 | ATM (0.77) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL29951738 | 0.82 | CTRB1 (0.49) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL1764220 | 0.81 | CTRB1 (0.48) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL1764214 | 0.81 | CTRB1 (0.48) | ATMCTRB1CTSLCTSSALDH1A1 | |
| SCHEMBL17765000 | 0.81 | ATM (0.67) | ATMCTRB1CTSLCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |