Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860031 | 0.84 | LMNA (0.56) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7179302 | 0.76 | KMT2A (0.50) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10957778 | 0.74 | KMT2A (0.49) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7186115 | 0.74 | KMT2A (0.49) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10957573 | 0.74 | RAB9A (0.41) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21929657 | 0.73 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15689106 | 0.73 | NPC1 (0.73) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23723568 | 0.71 | SLC12A5 (0.48) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8627107 | 0.71 | MEN1 (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1069018 | 0.71 | LMNA (0.46) | LMNAKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224919-B1 | NEW THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4742057-A | Antiallergic thiazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0224919-A2 | New thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |