Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309704 | 0.70 | DRD2 (0.42) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL28061014 | 0.69 | DRD2 (0.38) | DRD2DRD3HTR1A | |
| SCHEMBL4265708 | 0.68 | DRD2 (0.38) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL28769496 | 0.66 | DRD2 (0.35) | DRD2DRD3HTR1A | |
| SCHEMBL28946470 | 0.63 | DRD2 (0.38) | DRD2DRD3 | |
| SCHEMBL28679348 | 0.62 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL27793747 | 0.62 | DRD2 (0.44) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL8538844 | 0.62 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL4536932 | 0.62 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1626963 | 0.62 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875713-B2 | affinity pairs that can be efficiently utilized without being limited by factors such as chemical versatility, stability, irreversibility; for affinity chromatography, affinity labeling, immobilization, bioconjugation, immunohistochemical staining, flow cytometry, in situ hybridization, genetic mapping | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2011-01-25 | — | — | US | disclosed |
| US-20060292570-A1 | Novel synthetic binding pairs and uses thereof | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060292570-A1 | Novel synthetic binding pairs and uses thereof | DBNL, GEMIN5, PICALM | DRD2 597/4885DRD3 771/4885HTR1A 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.