Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836230 | 0.88 | SMN1; SMN2 (0.46) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27309652 | 0.81 | MEN1 (0.43) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL27313983 | 0.79 | KDM4E (0.49) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL27522368 | 0.78 | MAPT (0.46) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9835865 | 0.76 | USP2 (0.48) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL9833989 | 0.76 | RXFP1 (0.41) | PKMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9835593 | 0.76 | NPSR1 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL2015592 | 0.75 | HTT (0.62) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9835414 | 0.74 | MAPT (0.42) | SMN1; SMN2NPC1RAB9ACYP2C19ALDH1A1 | |
| SCHEMBL9836062 | 0.73 | NAPRT (0.47) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| CN-86108416-A | Oxazolidinedione derivative, process for producing the same, and herbicide containing the same | — | 1987-07-29 | — | — | CN | disclosed |