SCHEMBL9835593

SCHEMBL9835593

C=C(C)C(OC(=O)Nc1ccc(F)cc1Cl)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
ALOX15 P16050 8/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.40
SHMT2 P34897 1/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PYGL P06737 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836230 0.88 SMN1; SMN2 (0.46) NPSR1ALDH1A1
SCHEMBL9834529 0.88 USP2 (0.50) KMT2AMEN1ALDH1A1
SCHEMBL9833989 0.85 RXFP1 (0.41) NPSR1KMT2AMEN1ALDH1A1
SCHEMBL27522368 0.85 MAPT (0.46) KMT2AMEN1SHMT2ALDH1A1
SCHEMBL9835398 0.82 SMN1; SMN2 (0.49) KMT2AMEN1ALDH1A1
SCHEMBL9836972 0.81 MAPT (0.50) KMT2AMEN1ALDH1A1
SCHEMBL9836882 0.80 EPHX1 (0.46) NPSR1KMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL9835566 0.79 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL9837587 0.79 LMNA (0.47) NPSR1KMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL9835450 0.79 NPSR1 (0.43) NPSR1KMT2AMEN1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed