SCHEMBL983438

SCHEMBL983438

Sc1nnc(CCCc2nnc(S)o2)o1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12716534 0.95 MAPT (0.46) MAPTTSHR
SCHEMBL12716524 0.89 MAPT (0.34) MAPT
Potassium Ion SCHEMBL11557856 0.64
SCHEMBL21872329 0.57
SCHEMBL14557100 0.53 HPGD (0.39) TSHR
SCHEMBL13977896 0.41
SCHEMBL23149820 0.31
SCHEMBL13834573 0.31
SCHEMBL11319189 0.28
SCHEMBL23149826 0.28

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276793-B1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INT (FR) 2012-08-01 EP claimed
US-8063237-B2 Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-11-22 US claimed
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2011-03-31 US claimed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 EP claimed
US-7867577-B2 hydrolyzed, concentrated, and heated polysulfides, alkenyl silanes such as vinyltrimethoxysilane; for formation of lenses ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-01-11 US claimed
US-20090287015-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 US claimed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 WO claimed
CN-114231078-B Metal oxide microparticle dispersion and curable composition containing same 山阳色素株式会社 2024-08-27 CN disclosed
US-11365320-B2 Liquid polymerizable composition comprising chain-growth and step-growth polymerization monomers and inorganic nanoparticles dispersed therein, and its use to manufacture an optical article ESSILOR INTERNATIONAL (FR) 2022-06-21 US disclosed
CN-114231078-A Metal oxide microparticle dispersion and curable composition containing same 山阳色素株式会社 2022-03-25 CN disclosed
EP-3390542-B1 LIQUID POLYMERIZABLE COMPOSITION COMPRISING CHAIN-GROWTH AND STEP-GROWTH POLYMERIZATION MONOMERS AND INORGANIC NANOPARTICLES DISPERSED THEREIN, AND ITS USE TO MANUFACTURE AN OPTICAL ARTICLE ESSILOR INT (FR) 2021-10-06 EP disclosed
US-20180362772-A1 IQUID POLYMERIZABLE COMPOSITION COMPRISING CHAIN-GROWTH AND STEP-GROWTH POLYMERIZATION MONOMERS AND INORGANIC NANOPARTICLES DISPERSED THEREIN, AND ITS USE TO MANUFACTURE AN OPTICAL ARTICLE ESSILOR INTERNATIONAL (FR) 2018-12-20 US disclosed
EP-3390542-A1 LIQUID POLYMERIZABLE COMPOSITION COMPRISING CHAIN-GROWTH AND STEP-GROWTH POLYMERIZATION MONOMERS AND INORGANIC NANOPARTICLES DISPERSED THEREIN, AND ITS USE TO MANUFACTURE AN OPTICAL ARTICLE Essilor International (FR) 2018-10-24 EP disclosed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 EP disclosed
US-7867577-B2 hydrolyzed, concentrated, and heated polysulfides, alkenyl silanes such as vinyltrimethoxysilane; for formation of lenses ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-01-11 US disclosed
US-20100099683-A1 COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-04-22 US disclosed
US-20100099683-A1 COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-04-22 US disclosed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 WO disclosed
US-20090287015-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 US disclosed
WO-2007099108-A1 METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2007-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS TST, LAGE3, PSME1 MAPT 1086/4885TSHR 3396/4885
US-20100099683-A1 COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER LIG1, LIG4, LIG3 MAPT 3367/4885TSHR 4461/4885
US-20090287015-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS LAGE3, TST, PSME1 MAPT 758/4885TSHR 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.