Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.51 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.49 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GMNN | O75496 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833428 | 1.00 | GPR84 (0.51) | GPR84ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL2823597 | 0.86 | ZDHHC7 (0.58) | GPR84ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL2823595 | 0.86 | ZDHHC7 (0.58) | GPR84ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL2823598 | 0.86 | ZDHHC7 (0.58) | GPR84ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL29272710 | 0.84 | ZDHHC7 (0.68) | GPR84ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL20398338 | 0.83 | GPR84 (0.49) | GPR84FAAHFFAR1FFAR4MAPK1 | |
| SCHEMBL20398330 | 0.83 | GPR84 (0.49) | GPR84FAAHFFAR1FFAR4MAPK1 | |
| SCHEMBL23361766 | 0.80 | GPR84 (0.56) | GPR84ZDHHC7FFAR1FFAR4MAPK1 | |
| SCHEMBL9784116 | 0.80 | GPR84 (0.56) | GPR84ZDHHC7FFAR1FFAR4MAPK1 | |
| SCHEMBL6374127 | 0.80 | GPR84 (0.56) | GPR84ZDHHC7FFAR1FFAR4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223916-B1 | MULTIFUNCTIONAL THIADIAZOLE LUBRICANT ADDITIVES | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4990652-A | Alpha-brominated half esters or amides of succinic acid | ATOCHEM NORTH AMERICA, INC. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4902804-A | IMPROVED EXTREME PRESSURE, ANTIWEAR, ANTIOXIDANT AND ANTICORROSION PROPERTIES | PENNWALT CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0223916-A1 | Multifunctional thiadiazole lubricant additives | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1987-06-03 | — | — | EP | disclosed |