Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.54 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | GMNN | O75496 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823595 | 1.00 | ZDHHC7 (0.58) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL2823597 | 1.00 | ZDHHC7 (0.58) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL29272710 | 0.89 | ZDHHC7 (0.68) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9834524 | 0.86 | GPR84 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9833428 | 0.86 | GPR84 (0.51) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9069861 | 0.85 | ZDHHC7 (0.64) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9069864 | 0.85 | ZDHHC7 (0.64) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL5975489 | 0.85 | ZDHHC7 (0.64) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL21550736 | 0.83 | GPR84 (0.54) | ZDHHC7GPR84MAPK1GMNNLMNA | |
| SCHEMBL21550757 | 0.83 | GPR84 (0.54) | ZDHHC7GPR84MAPK1GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203434-B1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI HOLDINGS CO LTD (KR) | 2012-08-29 | — | — | EP | disclosed |
| US-8242288-B2 | Method of preparing (6R)-3-hexyl-4-hydroxy-6-undecyl-5, 6-dihydropyran-2-one, and intermediate used in the method | HANMI HOLDINGS CO., LTD. (KR) | 2012-08-14 | — | — | US | disclosed |
| US-20100274029-A1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5, 6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI PHARM. CO., LTD. (KR) | 2010-10-28 | — | — | US | disclosed |
| EP-2203434-A2 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | Hanmi Pharm. Co., Ltd. (KR) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009057938-A2 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI PHARM. CO., LTD. (KR) | 2009-05-07 | — | — | WO | disclosed |
| CN-1680347-A | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-ketone | ROCHE COLORADO CORP (CH) | 2005-10-12 | — | — | CN | disclosed |
| CN-1396919-A | Synthesis method of 3, 6-dialkyl-5, 6-dihydro-4-hydroxy-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2003-02-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274029-A1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5, 6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | DHCR7, DHPS, CYP8B1 | ZDHHC7 387/4885LCK 2855/4885PPARD 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.