Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833701 | 0.90 | CCKBR (0.56) | CCKBRCCKAR | |
| SCHEMBL9833697 | 0.90 | CCKBR (0.56) | CCKBRCCKAR | |
| SCHEMBL9834282 | 0.87 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL9833617 | 0.84 | CCKBR (0.69) | CCKBRCCKAR | |
| SCHEMBL23270828 | 0.83 | SCN9A (0.63) | — | |
| SCHEMBL8939508 | 0.83 | SCN9A (0.63) | — | |
| SCHEMBL31278511 | 0.83 | SCN9A (0.63) | — | |
| SCHEMBL25502042 | 0.82 | TACR1 (0.61) | — | |
| SCHEMBL31277956 | 0.82 | TACR1 (0.61) | — | |
| SCHEMBL28504493 | 0.82 | MPO (0.47) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442878-A4 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | — | 1991-10-23 | — | — | EP | disclosed |
| EP-0442878-A1 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-08-28 | — | — | EP | disclosed |
| WO-1989010355-A1 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0336356-A2 | Derivatives of tryptophan as CCK antagonists | ABBOTT LABORATORIES (US) | 1989-10-11 | — | — | EP | disclosed |