Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835310 | 0.87 | CYP3A4 (0.55) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9836380 | 0.86 | CYP3A4 (0.57) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9835428 | 0.86 | CYP3A4 (0.47) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9834615 | 0.85 | SLC6A1 (0.59) | KMT2ASLC6A1MEN1CYP3A4CYP2C9 | |
| SCHEMBL9835572 | 0.83 | SLC6A4 (0.45) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9837079 | 0.81 | KDM4E (0.44) | CYP3A4KDM2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9836009 | 0.81 | CYP3A4 (0.53) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9836372 | 0.80 | SLC6A4 (0.50) | CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9834327 | 0.74 | MEN1 (0.74) | KMT2ASLC6A1MEN1CYP3A4CYP2C9 | |
| SCHEMBL10692369 | 0.73 | KMT2A (0.53) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221572-B1 | N-SUBSTITUTED 3-PIPERIDINE-OR 3-PYRIDINE-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-09-25 | — | — | EP | claimed |